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PART ONE: QUESTIONS Introducing Developmental Biology

1. Comprehending Development: Generating New Cells and Organs

2. Differential Gene Expression in Development

3. Cell-Cell Communication in Development

PART TWO: SPECIFICATION Introducing Cell Commitment and Early Embryonic Development

4. Fertilization: Beginning a New Organism

5. Early Development: Rapid Specification in Snails and Nematodes

6. The Genetics of Axis Specification in Drosophila

7. Sea Urchins and Tunicates: Deuterostome Invertebrates

8. Early Development in Vertebrates: Amphibians and Fish

PART THREE: THE STEM CELL CONCEPT Introducing Organogenesis

9. Early Development in Vertebrates: Birds and Mammals

10. The Emergence of the Ectoderm: Central Nervous System and Epidermis

11. Neural Crest Cells and Axonal Specificity

12. Paraxial and Intermediate Mesoderm

13. Lateral Plate Mesoderm and the Endoderm

14. Development of the Tetrapod Limb

15. Sex Determination

16. Postembryonic Development: Metamorphosis, Regeneration, and Aging

PART FOUR: SYSTEMS BIOLOGY Expanding Developmental Biology to Medicine, Ecology, and Evolution

17. The Saga of the Germ Line

18. Birth Defects, Endocrine Disruptors, and Cancer

19. Ecological Developmental Biology: Biotic, Abiotic, and Symbiotic Regulation of Development

20. Developmental Mechanisms of Evolutionary Change

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